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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Microvasc Res. 2011 Apr 22;82(1):66–72. doi: 10.1016/j.mvr.2011.04.007

Figure 4.

Figure 4

A, B: Intravital fluorescence microscopy of FITC-labeled Staphylococcus aureus in postcapillary and collecting venules of the dorsal skinfold chamber (5 min after intra-arterial injection of bacteria) under physiological conditions. Note that blockade of gC1qR by application of MAb 74.5.2 (B) results in a significant reduction of bacterial adherence when compared to controls (A). Blue light epi-illumination; scale bars: 100μm. C: Adherent bacteria (mm−2) in venules of PBS-exposed dorsal skinfold chambers of Syrian golden hamsters, which were treated with MAb 74.5.2 (black bars; n = 6) or vehicle (control, white bars; n = 5), as assessed by intravital fluorescence microscopy and computer-assisted image analysis. Measurements were performed at 5, 10, 20, 30, and 60min after intra-arterial injection of the bacteria. Values are given as means ± SEM; *p<0.05 vs. control.