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. 2004 Jan 15;113(2):200–208. doi: 10.1172/JCI19639

Figure 3.

Figure 3

Generation of Hexb–/–FcRγ–/– mice. (a) PCR analysis of mouse tail DNA. From left lane: Hexb+/+FcRγ+/+, Hexb–/–FcRγ+/+, Hexb–/–FcRγ+/–, and Hexb–/–FcRγ–/– mice. (b) Clinical appearance of Hexb–/–FcRγ+/+ and Hexb–/–FcRγ–/– mice at 14 weeks. (c) Investigation of the titers of anti-GA2 antibodies in 14-week-old mice. Anti-GA2 antibody was at lower levels in Hexb–/–FcRγ–/– mice than in Hexb–/–FcRγ+/+ mice. n = 5–10. *P < 0.05, Student’s t test.