Reduction in the neurodegeneration of Purkinje cells in Hexb–/–FcRγ–/– mice and 14-week-old Hexb–/–FcRγ+/+ mice, but not Hexb–/–FcRγ–/– or Hexb+/+FcRγ+/+, displayed neurodegeneration and shrinkage of nuclei in Purkinje cells. Arrows indicate nuclei of Purkinje cells. H&E stain, original magnification, ×100. PI stain, original magnification, ×600. ML, molecular layer, Pc, Purkinje cells, GL, granular layer.