Figure 9.

IgG deposition in the cerebellar neurons of an SD patient. (a and b) H&E staining of cerebellar sections showed cells with typical ballooning. Arrows indicate enlarged cells with ganglioside storage. (c and d) Immunohistochemical staining of the cerebellum with alkaline phosphatase–labeled anti-IgG antibody. Arrows indicate cells with IgG deposition (stained as red). (a and c) Original magnification, ×200; (b and d) Original magnification, ×400. ML, molecular layer; Pc, Purkinje cells; GL, granular layer.