TABLE 1.
Blood metabolic and inflammatory parameters
| Lean |
Obese before surgery |
Obese after surgery |
|
|---|---|---|---|
| 6 females, 2 males | 11 females, 2 males | ||
| Age (years) | 29.5 ± 4 | 34.0 ± 10 | |
| BMI (kg/m2) | 20.9 ± 2.4 | 39.1 ± 1.9* | 28.1 ± 2.8*§ |
| WC (cm) | 72.2 ± 9.2 | 110.3 ± 9.9* | 89.7 ± 8.7*§ |
| HC (cm) | 91.3 ± 7.3 | 127.0 ± 5.2* | 105.0 ± 7.5*§ |
| Glucose (mg/dL) | 80.6 ± 3.1 | 84.3 ± 6.1 | 77.9 ± 7.3 |
| HbA1c (%) | 4.8 ± 0.2 | 5.2 ± 0.3 | 5.1 ± 0.3 |
| Insulin (pmol/L) | 25.0 ± 10.3 | 68.7 ± 38.1* | 21.5 ± 10.4§ |
| HOMA-IR | 0.7 ± 0.3 | 2.1 ± 1.2* | 0.6 ± 0.2§ |
| Cholesterol (mg/dL) | 189 ± 28 | 153 ± 24 | 141 ± 16 |
| HDL (mg/dL) | 74.5 ± 25.7 | 36.9 ± 5.8* | 52.6 ± 9.1*§ |
| LDL (mg/dL) | 99.5 ± 22.4 | 97.6 ± 26.4 | 73.6 ± 16.1 |
| Triglycerides (mg/dL) | 75.5 ± 38.9 | 94.1 ± 27.1 | 76.6 ± 19.9 |
| CRP (mg/dL) | 0.13 ± 0.02 | 0.91 ± 0.70* | 0.17 ± 0.02§ |
| ESR (mm/1 h) | 14 ± 12 | 26 ± 16* | 16 ± 9§ |
| Adiponectin (μg/mL) | 6.9 ± 1.7 | 2.7 ± 1.8* | 7.8 ± 1.6§ |
| Leptin (ng/mL) | 21.4 ± 6.2 | 36.8 ± 12.0* | 17.0 ± 13.9§ |
| TNF-α (pg/mL) | 5.8 ± 5.5 | 25.6 ± 10.3* | 12.4 ± 9.8§ |
| IL-1β (pg/mL) | 2.0 ± 1.8 | 42.9 ± 26.7* | 13.6 ± 4.3*§ |
| IL-6 (pg/mL) | 4.1 ± 4.2 | 26.3 ± 10.2* | 8.5 ± 6.4§ |
| IL-10 (pg/mL) | 14.0 ± 10.1 | 15.6 ± 16.5 | 15.8 ± 5.5 |
CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; HC, hip circumference; HOMA-IR, homeostasis model assessment of insulin resistance; WC, waist circumference.
*P < 0.05 vs. lean.
§P < 0.05 vs. obese before surgery.