Table 1.
Clinical and metabolic features of the VNDS population
| Variable | Male | Female | All |
|---|---|---|---|
| n (M/F) | 342 | 167 | 509 |
| Age (years) | 58 [51–65] | 61 [55–66] | 59 [52–65] |
| BMI (kg/m2) | 28.7 [26.2–32.4] | 30.8 [27.4–34.5] | 29.4 [26.5–33.2] |
| Waist (cm) | 102 [94–112] | 97 [91–104] | 100 [93–108] |
| Fasting P-glucose (mmol/L) | 7 [6.2–8.0] | 7.3 [6.2–8.1] | 7.1 [6.2–8.0] |
| 2-h P-glucose (mmol/L) | 13.7 [11.0–16.4] | 13.3 [10.2–16.3] | 13.5 [10.6–16.3] |
| HbA1c (%) | 6.7 [6.1–7.6] | 6.7 [6.2–7.4] | 6.7 [6.2–7.5] |
| Triglycerides (mmol/L) | 1.4 [1.0–2.1] | 1.3 [1.0–2.0] | 1.4 [1.0–2.0] |
| HDL cholesterol (mmol/L) | 1.1 [1.0–1.3] | 1.2 [1.0–1.4] | 1.1 [1.0–1.4] |
| Cholesterol (mmol/L) | 4.9 [4.2–5.5] | 5.1 [4.5–5.8] | 5.0 [4.3–5.6] |
| Systolic blood pressure (mmHg) | 134 [120–150] | 140 [130–150] | 138 [124–150] |
| Diastolic blood pressure (mmHg) | 82 [80–90] | 85 [80–90] | 84 [80–90] |
| Insulin sensitivity (μmol/min/m2 BSA) | 565 [314–834] | 546 [394–755] | 559 [351–800] |
| Insulinogenic index (mU/mmol) | 3.5 [2.0–5.8] | 4.6 [2.3–8.1] | 3.8 [2.0–6.7] |
| CIR120’ (mU × L/mmol2) | 0.4 [0.2–1.1] | 0.6 [0.2–1.4] | 0.5 [0.2–1.2] |
| eGFR (mL/min/1.73 m2) | 84.4 [74.7–96.3] | 74.9 [62.5–86.1] | 80.0 [70.3–93.4] |
| Urinary albumin/creatinine (mg/mmol) | 0.8 [0.4–3.1] | 0.6 [0.3–1.5] | 0.8 [0.4–2.5] |
| Serum creatinine (μmol/L) | 82 [74–90] | 69 [62–80] | 79 [68–88] |
Data are presented as median [interquartile range].