Table 2.

Results of multiple logistic regression of acute cardiovascular events as a function of hypoglycemic events^*

Independent variables	Patients of all ages† with type 2 diabetes		Patients aged ≥65 years‡ with type 2 diabetes
	Odds ratio	95% CI	Odds ratio	95% CI
Coded HE in evaluation period	1.79	1.69–1.89	1.78	1.65–1.92
Age 65+ vs. 18–34 years	13.26	9.64–18.25	—	—
Age 55–64 vs. 18–34 years	9.79	7.11–13.47	—	—
Age 45–54 vs. 18–34 years	6.79	4.92–9.35	—	—
Age 35–44 vs. 18–34 years	3.54	2.54–4.94	—	—
Male vs. female	1.56	1.52–1.61	1.39	1.34–1.45
West vs. Northeast	0.82	0.77–0.88	0.86	0.79–0.93
Unknown vs. Northeast	0.97	0.73–1.29	0.80	0.42–1.50
South vs. Northeast	1.09	1.03–1.15	1.05	0.97–1.13
North Central vs. Northeast	1.19	1.13–1.26	1.16	1.08–1.24
Peripheral vascular disease	1.29	1.20–1.38	1.21	1.11–1.32
Chronic kidney disease	1.17	1.10–1.25	1.16	1.07–1.26
Diabetic peripheral neuropathy	1.10	1.03–1.18	—	—
Diabetic retinopathy	1.33	1.23–1.44	1.24	1.11–1.38
Deyo–Charlson comorbidity index	1.05	1.04–1.06	1.05	1.04–1.07
Total baseline expenditures	1.76	1.70–1.83	1.56	1.48–1.64
Prior cardiovascular events	2.87	2.73–3.02	2.39	2.22–2.56

^*Dependent variable = ACVEs in the evaluation period; models fit using backward stepwise selection of variables with P < 0.01.

^†Observations = 860,583; max-rescaled R² = 0.0651.

^‡Observations = 316,695; max-rescaled R²= 0.0322.