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Summary of DmOctα1Rb signaling. A) Cartoon of a GPCR. Phosphorylation and dephosphorylation of T352 in the third intracellular loop of DmOctα1Rb cause desensitization and resensitization of receptor activity, respectively. B) Respective enzymatic activity of PKC and cellular phosphatases is depicted in a representative Ca2+ imaging trace of a DmOctα1Rb-expressing cell activated with 50 nM octopamine.
