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. 2010 Sep 15;137(18):3025–3035. doi: 10.1242/dev.049528

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Fig. 1. — Jag2 expression during embryonic development of molars and incisors. In situ hybridisation on longitudinal (A,E,J) and frontal (B-D,F-I) cryosections of E11.5-18.5 mouse embryos. Shown are the first molar (A-E) and incisor (F-J) tooth germs, and mandibular (F,I,J) and maxillary (G,H) incisors. (A) Jag2 expression in E11.5 dental epithelium (de) and oral epithelium (oe). (B,C) Jag2 transcripts in E12.5 (B) and E13.5 (C) dental bud epithelium (de), in cells juxtaposed to the underlying mesenchyme (m). (D) Jag2 expression in inner dental epithelium (ide) cells of cap stage molars (E15.5). Expression is downregulated in oral epithelium and outer dental epithelium (ode). (E) Jag2 expression in inner dental epithelium of bell stage molars (E18.5). (F,G) Jag2 expression in the epithelium of E12.5 (F) and E13.5 (G) incisors. (H-J) Jag2 expression in E15.5 (H) and E17.5 (I,J) incisors in inner dental epithelium cells. Ant, anterior part of the incisor; cl, cervical loop; d, dentin; df, dental furrow; dp, dental papilla or dental pulp; md, mandibular process; mx, maxillary process; ne, nasal epithelium; ode, outer dental epithelium; Post, posterior part of the incisor; si, stratum intermedium; sr, stellate reticulum; t, tongue.