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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Genet Epidemiol. 2011 May 18;35(5):398–409. doi: 10.1002/gepi.20588

Table 3.

P values for the association of rare variants in four RAS genes with hypertension in the WTCCC dataset. The weights for SWSS were calculated based on affected sibpairs in the FHS dataset.

Gene # of SNP SPWSS ORWSS WSS HG
ACE 3 0.877 0.893 1.0 1.0
AGT 8 2.56×10-3 4.76×10-3 0.556 0.011
AGT1 6 6.91×10-4 4.97×10-3 0.492 -
AGTR1 45 0.147 0.972 0.356 0.36
REN 4 0.265 0.432 1.0 1.0
1

rs7549009 and rs4628514 were excluded because of the perfect LD with rs7555650.