Table 2.

Overall distribution of PRNP regulatory region rare alleles and risk of sporadic CJD

PRNP SNP	Cases (%)	Controls (%)	OR (95% CI)	P- value	OR (95% CI) *	P- value*
-101G carriers	28 (22.8)	25(20.3)	0.9 (0.5-1.6)	0.64	0.98 (0.52-1.83)	0.95
-101G non carriers	95 (77.2)	98 (79.7)
310C carriers	17(13.0)	18 (9.3)	1.5 (0.7-2.9)	0.30	2.4 (1.1-5.4)	0.03
310C non carriers	114 (87.0)	176 (90.7)
385C carriers	5 (4.3)	7 (5.4)	1.3 (0.4-4.1)	0.70	0.69 (0.21-2.29)	0.54
385C non carriers	111 (95.7)	123 (94.6)

* Adjusted by PRNP M129V polymorphism