Table 3.

Distribution of PRNP 310C allele, stratified by PRNP M129V genotypes, and risk of sporadic CJD

PRNP M129V genotype	PRNP SNP	Cases (%)	Controls (%)	OR (95% CI)	P- value*
Methionine/methionine	310C Carriers	8 (8.2)	1 (1.2)	7.2 (0.9-58.8)	0.04
	Non carriers	90 (91.8)	81 (98.6)
Methionine/valine	310C Carriers	4 (23.5)	12 (13.0)	2.1 (0.6-7.3)	0.27
	Non carriers	13 (76.5)	80 (87.0)
Valine/valine	310C Carriers	5 (31.3)	5 (25.0)	1.4 (0.3-5.9)	0.72
	Non carriers	11 (68.8)	15 (75.0)

*Two sided Fisher's exact test