Table 2.
MRI Parameter | Ipsilateral Thalamus | Contralateral Thalamus | Right Thalamus in controls | ||||
---|---|---|---|---|---|---|---|
W1 | W4 | W12 | W1 | W4 | W12 | ||
MD(×10-3mm2/s) | 0.877 ± 0.059a | 0.863 ± 0.051c | 0.954 ± 0.074abcd | 0.866 ± 0.046a | 0.872 ± 0.044a | 0.869 ± 0.043a | 0.837 ± 0.047 |
FA | 0.332 ± 0.077 | 0.321 ± 0.063 | 0.315 ± 0.075 | 0.344 ± 0.046 | 0.352 ± 0.048 | 0.349 ± 0.058 | 0.349 ± 0.053 |
NAA | 12911 ± 1592a | 11139 ± 1943abc | 9365 ± 1703abcd | 13471 ± 1632 | 13220 ± 1830 | 13788 ± 1298 | 13946 ± 1693 |
Cho | 8907 ± 1294 | 8893 ± 1963 | 8848 ± 1689 | 9762 ± 2397 | 9008 ± 1700 | 9343 ± 963 | 9502 ± 2331 |
Cr | 7808 ± 1310 | 7585 ± 1539 | 7213 ± 1288 | 7995 ± 1317 | 7955 ± 1064 | 7751 ± 716 | 7933 ± 1494 |
ROI: region of interest; MD: mean diffusivity; FA: fractional anisotropy; NAA: N-acetylaspartate; Cho: choline; Cr: creatine; W1: the first week; W4: the fourth week; W12: the twelfth week.
aP< 0.05, Student's t test, compared to the control group; bP< 0.05, Student's t test, compared to contralateral thalamus in patient group at the same time point; cP< 0.05, Tukey test, compared to W1 in ipsilateral thalamus; dP< 0.05, Tukey test, compared to W4 in ipsilateral thalamus.