Table 1. Functional annotation of genes that were differentially expressed due to the effects of the lesion.

Category	Term	P-value
Biological process	Cell death	0.0074
	Acute inflammatory response	0.014
	Actin filament depolymerization	0.028
	Metal ion transport	0.034
Cellular component	Cytoskeleton	0.0021
	Intrinsic to plasma membrane	0.031
Molecular function	Metal ion transmembrane transporter	0.007

GO analysis of the 24 differentially expressed genes that were changed solely due to the injection of KA. Enriched functional categories associated with the lesion were mostly related to cell death and inflammation, which is consistent with the expected effects of the KA injection.