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. Author manuscript; available in PMC: 2011 Nov 15.
Published in final edited form as: Mov Disord. 2010 Nov 15;25(15):2654–2657. doi: 10.1002/mds.23256

Table 2.

Odds ratios (ORs) and 95% confidence interval (CI ) of Parkinson’s disease according to restless legs syndrome status in the Health Professional Follow-up Study

No RLS (n=22175) RLS 5-14 times/mo (n=549) RLS 15+ times/mo (n=395) P trend
# cases 132 4 9
Age adjusted OR 1(ref.) 1.10 (0.40, 2.98) 3.24 (1.63,6.44) 0.002
Multivariate adjusted OR1 1(ref.) 1.10 (0.41, 3.03) 3.09 (1.54,6.19) 0.003

Logistic regression models were used to calculate ORs, adjusted for age (in years), smoking status (never smoker, former smoker, or current smoker: cigarettes/d, 1-14 or ≥15), BMI (<23, 23-24.9, 25-26.9, 27-29.9, or ≥30 kg/m2), use of antidepressant drugs (yes/no), physical activity (quintiles), the Crown-Crisp phobic anxiety index (0-1, 2, 3, or ≥4) and presence of stroke, hypertension, or myocardial infraction (each of them, yes/no)