Table 2.
Period | Immunogen | Host | Protection (%), Max (Range) |
---|---|---|---|
1973–1989 | Live attenuated mc | Goat, cattle, sheep | 86 (29–86) |
1972–1985 | Crude antigen | ||
Sonicated cultures | Sheep | 79 | |
Freez driedSAg | Rats | 41–55 | |
Immature fluke E SAg | Rabbits | Significant | |
1973–1981 | Passive immunization (Immune Sera) | Rats | 25–48 |
Rabbits | |||
1990–1996 | Defined antigens | ||
GST | Cattle | 18–69 | |
FABP | Cattle | 55 | |
Cathepsin L | Sheep | 69 | |
Cattle | 42–69 | ||
Cathepsin L + fluke haemoglobin | Cattle | 52–72 |