Table 5.

Immunoprotection against fasciolosis using purified immunogens

Parasite	Host	Protein	Vaccine protection	References
F. hepatica	Cattle	FABP	55%	Hillyer et al. (1987)
F. hepatica	Sheep	GST	57%	Sexton et al. (1990)
F. hepatica	Cattle		19–69%	Morrison et al. (1996)
F. gigantica	Cattle		18% (ns)	Estuningsih et al. (1997)
F. hepatica	Sheep	Cathepsin L	69% (FEC)	Wijffles et al. (1994)
F. hepatica	Cattle		42–69%	Dalton et al. (1996)
F. hepatica	Cattle	Haemoglobin	44%	Dalton et al. (1996)
F. hepatica	Cattle	Cathepsin L + Haemoglobin	52–78%	Dalton et al. (1996)
F. hepatica	Sheep	Cysteine proteinase	No difference in worm burden	Wijffles et al. (1994)
F. hepatica	Cattle	Defined	55% less fluke eggs	Hillyer (1984)
F. gigantica	Rats	32 kDa NEJ protein	90% protection	Florine et al. (2000)

NEJ Newly existed juvenile fluke, FEC Faecal egg counts