Table 2.
Possible mechanisms of mitochondrial dysfunction in pathological hypertrophy
| Potential mechanisms of mitochondrial dysfunction in pathological hypertrophy |
|---|
| ROS |
| Altered ANT expression |
| Cardiolipin loss or peroxidation |
| Fatty acid and lipid overload |
| Mitochonrial uncoupling |
| Impaired mitochondrial biogenesis |
| Reduced transcriptional signalling of regulators of mitochondria |