Table 2.
Possible mechanisms of mitochondrial dysfunction in pathological hypertrophy
Potential mechanisms of mitochondrial dysfunction in pathological hypertrophy |
---|
ROS |
Altered ANT expression |
Cardiolipin loss or peroxidation |
Fatty acid and lipid overload |
Mitochonrial uncoupling |
Impaired mitochondrial biogenesis |
Reduced transcriptional signalling of regulators of mitochondria |