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. 2011 Apr 1;34(2):298–303. doi: 10.1590/S1415-47572011005000001

Table 2-.

DNA migration in the comet assay for the assessment of genotoxicity of Cotinus coggygria extract in the livers of albino wistar rats, 24 and 72 h after treatment.

Treatments Levels of damage
Total score (mean ± SD)
0 1 2 3 4
Negative control 84.1 ± 1.32 10.6 ± 0.40 6.30 ± 0.3 0.00 ± 0.00 0.00 ± 0.00 23.20 ± 1.10
C. coggygria 24 h
500 mg/kg 78.8 ± 0.42 15.6 ± 0.44 5.60 ± 0.16 0.00 ± 0.00 0.00 ± 0.00 26.80 ± 2.30
1000 mg/kg 43.8 ± 0.33 32.8 ± 0.20 17.7 ± 0.40 4.70 ± 0.40 1.00 ± 0.21 86.30 ± 0.83*
2000 mg/kg 27.2 ± 0.26 38.8 ± 0.34 25.7 ± 0.39 6.10 ± 0.19 2.01 ± 0.21 116.50 ± 1.14*
C. coggygria 72 h
500 mg/kg 81.0 ± 0.84 13.4 ± 0.16 5.70 ± 0.84 0.00 ± 0.00 0.00 ± 0.00 24.80 ± 0.45
1000 mg/kg 41.6 ± 0.26 45.0 ± 0.42 10.1 ± 0.18 3.10 ± 0.24 0.00 ± 0.00 74.50 ± 1.14*
2000 mg/kg 30.4 ± 0.32 47.2 ± 0.35 16.6 ± 0.37 2.90 ± 0.24 1.03 ± 0.25 92.10 ± 1.22*
*

Significantly different from the negative control p < 0.05.