Table 3-.

DNA migration in the comet assay for the assessment of genotoxicity of Cotinus coggygria extract in bone marrow of albino wistar rats, 24 and 72 h after treatment.

Treatments	Levels of damage					Total score (mean ± SD)
	0	1	2	3	4
Negative control	79.8 ± 0.41	20.2 ± 0.35	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	21.0 ± 1.60
C. coggygria 24 h
500 mg/kg	76.4 ± 0.48	20.4 ± 0.43	3.20 ± 1.51	0.00 ± 0.00	0.00 ± 0.00	26.8 ± 0.24
1000 mg/kg	31.1 ± 0.41	40.2 ± 0.28	19.8 ± 0.38	7.40 ± 0.36	1.50 ± 0.47	108.0 ± 0.65*
2000 mg/kg	27.4 ± 0.48	32.1 ± 0.27	30.2 ± 0.33	6.60 ± 0.20	3.80 ± 0.42	127.5 ± 0.43*
C. coggygria 72 h
500 mg/kg	72.2 ± 0.58	27.7 ± 0.47	0.00 ± 0.00	0.00 ± 0.00	0.00 ± 0.00	25.2 ± 1.90
1000 mg/kg	42.3 ± 0.42	47.3 ± 0.43	8.70 ± 0.40	1.90 ± 0.42	0.00 ± 0.00	70.4 ± 1.50*
2000 mg/kg	27.2 ± 0.40	49.5 ± 0.45	19.10 ± 0.2	3.20 ± 0.23	1.01 ± 0.26	101.3 ± 3.60*

^*Significantly different from the negative control p < 0.05.