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Interplay between the bacterial virulence and host defense systems during nuclear import, chromatin targeting and proteasomal uncoating of the Agrobacterium T-complex. (A) Activation of infectivity and defense. (B) Transfer of the T-complex and Vir effectors into the host cell. (C) Nuclear import of the T-complex via MPK3-depenent nuclear import of VIP1. (D) Chromatin targeting and proteasomal uncoating of the T-complex by VIP1 and VBF. For details, see text.
