Table 6; online.
Neural tube defects (NTDs) occurring in pregnancies where mothers who took folic acid
| SEX1 | RACE2 | |||||||
|---|---|---|---|---|---|---|---|---|
| TYPE OF DEFECT | # OF CASES | M | F | U | W | B | H | O |
| Isolated | 107 (76.4%) | 46 (32.9%) | 43 (30.7%) | 18 (12.9%) | 89 (63.6%) | 15 (10.7%) | 2 (1.4%) | 1 (0.7%) |
| Spina bifida | 50 (35.7%) | 26 | 17 | 7 | 40 | 9 | 1 | 0 |
| Anencephaly | 46 (32.9%) | 16 | 22 | 8 | 41 | 4 | 1 | 0 |
| Encephalocele | 11 (7.9%) | 4 | 4 | 3 | 8 | 2 | 0 | 1 |
| Associated Anomalies | 33 (23.6%) | 14 (10.0%) | 16 (11.4%) | 3 (2.1%) | 28 (20.0%) | 5 (3.6%) | 0 (0.0%) | 0 (0.0%) |
| OEIS3 | 3 (2.1%) | 3 | 0 | 0 | 3 | 0 | 0 | 0 |
| Trisomy 18 | 7 (5.0%) | 4 | 3 | 0 | 7 | 0 | 0 | 0 |
| Amniotic bands/cranial defects | 3 (2.1%) | 2 | 1 | 0 | 1 | 2 | 0 | 0 |
| Goldenhar | 1 (0.7%) | 0 | 1 | 0 | 1 | 0 | 0 | 0 |
| Chromosome aberrations | 5 (3.6%) | 1 | 4 | 0 | 4 | 1 | 0 | 0 |
| Other anomalies | 14 (10.0%) | 4 | 7 | 3 | 12 | 2 | 0 | 0 |
| TOTAL | 140 (100%) | 60 (43.0%) | 59 (42.0%) | 21 (15.0%) | 117 (83.6%) | 20 (14.3%) | 2 (1.4%) | 1 (0.7%) |
1
M=male, F=female, U=unknown
2
W=non-Hispanic white, B=non-Hispanic black, H=Hispanic, O=other
3
OEIS=Omphalocele, Exstrophy of the bladder, Imperforate anus, and Sacral meningomyelocele