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. Author manuscript; available in PMC: 2012 Jul 1.
Published in final edited form as: Addict Biol. 2011 Mar 11;16(3):440–449. doi: 10.1111/j.1369-1600.2010.00309.x

Figure 2.

Figure 2

SD rats self-administer 20% ethanol using an operant self-administration paradigm. (A.) Animals that were previously exposed to the intermittent-access, 20% ethanol two-bottle choice model (n=23) exhibited significantly higher intake levels in comparison to animals that were previously exposed to 10% ethanol (n=9). The values are expressed as the mean ethanol intake (g/kg/24hr) ± SEM (two-way ANOVA followed by Newman-Keuls post hoc test). Blood samples were collected from the lateral tail vein immediately following the 30-minute FR3 session for BEC determination. The amount of ethanol consumed for the 20% ethanol- and 10% ethanol-responding animals significantly correlated with the measured BECs (linear regression): 20% ethanol (B.): r2=0.6667, p<0.001; 10% ethanol (C.): r2=0.4782, p < 0.05. * p< 0.05, ** p<0.01, *** p<0.001, n=23 for the 20% ethanol group and n=9 for the 10% ethanol group.