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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Mol Microbiol. 2011 May 5;80(6):1530–1548. doi: 10.1111/j.1365-2958.2011.07665.x

Table 1.

Plaque formation, and hemolytic and phospholipase activities of domain swap mutants.

PrsA2 Chimeric Construct Plaque Size (% WT) Hemolytic Units Phospholipase Activity
PrsA2 (Full length) 100 +/− 3.16 100 +/− 9.5 +
PrsA1 (Full length) 20.2 +/− 0.98*** 31.8 +/− 4/4*** −
ΔprsA1ΔprsA2 20.0 +/− 2.10*** 37.5 +/− 3.5*** −
P2N-P1P-P1C 102.8 +/− 2.80 44.0 +/− 5.8*** +
P1N-P1P-P2C 23.3 +/− 3.40*** 88.0 +/− 8.0 −
P1N-P2P-P1C 72.5 +/− 1.30*** 40.8 +/− 4.2*** −
P2N-P2P-P1C 100.1 +/− 8.60 80.0 +/− 13.6 +
P1N-P2P-P2C 61.6 +/− 1.60*** 66.7 +/− 6.7 −
P2N-P1P-P2C 101.7 +/− 8.60 100 +/− 6.2 +

Statistical significance was calculated using a 1-way ANOVA with Tukey’s multiple comparison test. Statistically significant difference compared to PrsA2 (Full Length) (ΔprsA2 + pPL2- prsA2) are indicated (***, P< .0001)