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A) Typical oxygen tension traces showing inhibition of mitochondrial respiration by the combination of 25 μM nitrite and 20 μM of the indicated hemoglobins. A shorter time between lid removal (t = 120s) and increases in oxygen levels above zero imply higher degree of inhibition and hence NO formation. B) Summarized data showing the extent of mitochondrial respiration inhibition attained with the indicated hemoglobins. Data are means ± SEM, n = 5, * p <0.05.
