Table 1.
Patient demographics and baseline tumor characteristics for the FAS†
| Demographic/Characteristic | SG1 n = 66 |
SG2 n = 70 |
p-value |
|---|---|---|---|
| Age, yearsψ | 61 ± 12 | 56 ± 11 | 0.0181 |
|
| |||
| Female | 26 (39%) | 32 (46%) | 0.4912 |
|
| |||
| ECOG PS 0 | 56 (85%) | 61 (87%) | 0.8062 |
|
| |||
| Clinical Stage | 0.0531 | ||
| II | 22 (33%) | 13 (19%) | |
| III | 44 (67%) | 57 (81%) | |
|
| |||
| Pre-CRT T Stage | 0.1996 | ||
| T2 | 2 (3%) | 7 (10%) | |
| T3 | 63 (95%) | 62 (89%) | |
| T4 | 1 (2%) | 1 (1%) | |
|
| |||
| Pre-CRT N Stage | 0.0854 | ||
| N0 | 22 (33%) | 13 (18%) | |
| N1 | 42 (64%) | 53 (76%) | |
| N2 | 1 (2%) | 4 (6%) | |
| NX | 1 (2%) | 0 (0%) | |
|
| |||
| Distance from anal verge (cm)ψ | 6.9 ± 3.1 | 6.6 ± 3.1 | 0.5340 |
|
| |||
| Size (cm)* ψ | 4.4 ± 1.6 | 4.8 ± 2.0 | 0.2401 |
|
| |||
| Circumferential tumors | 12 (18%) | 25 (36%) | - |
*
Non-circumferential tumors;
ψ
Mean ± standard deviation;
†
Full analysis set as described in Figure 2. Abbreviations: ECOG PS - Eastern Collaborative Oncology Group Performance Status.