Figure 26A, B, C, D. Ultra-short Echo TIme MRI can be used to probe the deepest layer of cartilage, the calcified zone. Conventional MRI shows a signal void from this zone on T1- (A) and PD-weighted images (B), but uTE MRI (C) and UTE MRI with long T2 suppression (D) show signal from the calcified zone. This zone may be important in the development of OA (Courtesy of Christine Chung and Graeme Bydder, UCSD).