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DNA methylation changes at Ppara correlate with its expression. (A) Methylation of the Ppara SmaI/XmaI interval decreased in MD supplemented offspring at P30 and P90 (P30: n= 10–10, P= 0.041; P90: n= 8–8, P= 0.0083). (B) Ppara expression increased in MD supplemented offspring colonic mucosa at P90 (n= 10–10, P= 0.008). (C) Methylation at Ppara inversely correlates with expression (r = 0.79; P= 0.000034).
