Fig. 2.
Average TCORE (A) and HLI (B) in OVX + E2 and OVX rats exposed to ambient temperatures of 20, 24, or 31 C. A, At 20 and 24 C, the average core temperatures were not significantly different between the OVX + E2 and OVX animals. At the TAMBIENT of 31 C, the OVX rats (but not the OVX + E2 rats) exhibited a significant increase in TCORE compared with OVX rats at 20 and 24 C and OVX + E2 rats. B, HLI was significantly increased from 20 to 24 C and from 24 to 31 C in both the OVX + E2 and the OVX rats, reflecting increased skin vasodilatation at higher ambient temperatures. At all ambient temperatures, the OVX rats exhibited a significantly higher HLI than the OVX + E2 rats (n = 22–23 rats/group). Values represent means ± sem. *, Significant difference between OVX + E2 and OVX rats; #, significant effect of TAMBIENT in OVX rats; +, significant effect of TAMBIENT in OVX + E2 rats.