Table 1.
Subject characteristics.1
| Sepsis (n = 24) | Trauma (n = 33) | Combined group (n = 57) | |
|---|---|---|---|
| Age | 49.0 ± 16.5 | 38.4 ± 18.2 | 42.8 ± 18.1 |
| % male | 62.5 | 60.6 | 61.4 |
| % ARDS | 66.7 | 45.5 | 54.4 |
| % AHRF | 87.5 | 63.6 | 73.7 |
| % survival | 62.5 | 66.7 | 64.9 |
| Lung compliance at 0 h | 43.7 ± 12.0 | 45.0 ± 19.9 | 44.6 ± 17.4 |
| APACHE II 0–24 h | 23.8 ± 8.5 | 21.8 ± 9.3 | 22.6 ± 8.9 |
| CXR score 0 h | 2.0 ± 1.0 | 1.2 ± 1.1 | 1.5 ± 1.1 |
| PaO2/FiO2 at 0 h | 158.7 ± 92.3 | 254.5 ± 103.0 | 218.1 ± 108.8 |
| PaO2/FiO2 at 24 h | 181.3 ± 111.2 | 254.4 ± 97.6 | 225.5 ± 108.2 |
| ΔTFN 0–24 h | −14.5 ± 38.5 | 18.8 ± 62.5 | 4.7 ± 55.7 |
| ΔEIIIA + FN 0–24 h | 2.0 ± 1.9 | 6.8 ± 3.1 | 4.7 ± 3.6 |
| Risk-to-draw, all patients (h)2 | 16.8 ± 12.1 | 17.6 ± 7.0 | 17.3 ± 9.1 |
| Admit-to-draw, all patients (h)3 | 97.6 ± 135.0 | 15.0 ± 8.1 | 46.4 ± 91.5 |
| Risk-to-draw, patients analyzed for progression to ARDS or AHRF (n = 45) (h)4 | 16.8 ± 12.1 | 17.2 ± 6.9 | 17.0 ± 9.3 |
| Risk-to-draw, patients analyzed for survival (n = 34) (h)5 | 17.8 ± 12.7 | 18.3 ± 6.3 | 18.1 ± 9.1 |
Notes:
1
Data are expressed as the average ± standard deviation;
2
Risk-to-draw = the time in hours from initial diagnosis of either major trauma or sepsis syndrome to the time of the 0 h (first) blood draw. Data were available for 50 (19 sepsis and 31 trauma) patients;
3
Admit-to-draw = the time in hours from hospital admission to the 0 h (first) blood draw. Data were available for 50 (19 sepsis and 31 trauma) patients;
4
In this subgroup, data were available for 19 sepsis patients and 26 trauma patients;
5
In this subgroup, data were available for 13 sepsis patients and 21 trauma patients.