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. 2011 Feb 25;121(1):132–139. doi: 10.1093/toxsci/kfr046

TABLE 2.

Association of TNF-α (−308G>A) and IL10 (−3575 T>A) Polymorphisms with Arsenic-Induced Skin Lesions

Genotype Exposed individuals Exposed individuals
Without skin lesions With skin lesions OR
N (%) N (%) (95% CI) p Values
TNF-α (−308G>A)
GG 168 (88.4) 148 (71.6) 1.0 (Ref) < 0.001
GA/AA 22 (11.6) 59 (28.5) 3.04 (1.78–5.21)
IL10 (−3575 T>A)
TT 157 (83.2) 145 (71.1) 1.0 (Ref) 0.0046
TA/AA 33 (16.8) 62 (28.9) 2.03 (1.26–3.28)

Note. CI, confidence interval.