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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Stroke. 2011 Apr 21;42(6):1736–1741. doi: 10.1161/STROKEAHA.110.603811

Figure 2. WE treatment during MCAO improves neurological performance scores and reduces infarct size.

Figure 2

Mice were administered vehicle, WE (25 μg/kg), or tPA (2.5 mg/kg) during MCAO. A, Neurological deficits were scored 24 hours post-MCAO. Following scoring, autopsy was performed and brain sections were stained with TTC. B, Images of the sections were analyzed by morphometric analysis to determine the percentage of TTC-defined infarcted tissue. C, Representative images of brain sections show the presence of TTC-defined infarct (lighter areas) and viable tissue (darker areas). Values are mean±SEM, n=16-20. *P<0.05 versus vehicle treatment. #P<0.05 versus tPA.