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. Author manuscript; available in PMC: 2012 Jun 1.
Published in final edited form as: Stroke. 2011 Apr 21;42(6):1736–1741. doi: 10.1161/STROKEAHA.110.603811

Table 2. Plasma APTT and thrombin time measurements following administration of vehicle, WE or tPA.

Treatment APTT Thrombin time
Vehicle 25.2±0.9 13.6±0.5
WE 26.2±1.1 14.7±0.6
tPA 27.8±0.8 13.3±0.4

Anesthetized mice were administered a bolus of vehicle, WE (25 μg/kg), or tPA (2.5 mg/kg). Fifteen minutes after administration, blood was drawn into sodium citrate and plasma prepared by centrifugation. Plasma APTT and thrombin times were measured at 10.0±1.0 and 10.5±1.0 minutes, respectively, after the blood draw. Values are mean±SEM from 5-6 experiments.