. Author manuscript; available in PMC: 2012 Mar 1.

Published in final edited form as: Arthritis Rheum. 2011 Mar;63(3):573–586. doi: 10.1002/art.30129

Table 5.

ACR/EULAR definitions of remission in rheumatoid arthritis clinical trials.^*

Boolean Based Definition:

At any time point, patient must satisfy all of the following:

Tender Joint Count ≤1^†
Swollen Joint Count ≤1^†
CRP ≤1 mg/dL
Patient Global Assessment ≤1 (on a 0-10 scale)^§

Index Based Definition

At any time point, patient must have SDAI ≤3.3^**

For recommendations regarding remission in clinical practice settings, see Tables 2 A, B and text of the results and discussion sections.

^†

For tender and swollen joint counts, a 28 joint count may miss active joints especially in the feet and ankles and it is preferable to include feet and ankles also when evaluating remission.

^§

The following wording and response categories should be used for global assessment: Considering all of the ways your arthritis has affected you, how do you feel your arthritis is today? Verbal anchors for the response can range from ‘asymptomatic’ to ‘severe symptoms’.

^**

SDAI, Simplified Disease Activity Index is defined as the simple sum of the tender joint count (28), swollen joint count (28), patient global assessment (on a 0-10 scale), physician global assessment (on a 0-10 scale) and CRP (mg/dL).