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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Curr Protoc Mouse Biol. 2011;1:105–122. doi: 10.1002/9780470942390.mo100149

Table 1.

Mean arterial pressure (MAP) and heart rate (HR) in conscious and anesthetized mice

Type of
Anesthesia		 None
(Conscious)		 Avertin pentobarbital K+X isoflurane
Strain C57/B6SJL C57BL/6 Webster 4 C57/B6JSL Swiss, C57BL/6
MAP(mmHg) 103±1 75±2 89±2 64±3 79±3
HR(bpm) 588±14 431±15 514±17 297±15 544±31
Dose none 300mg/kg ip 60mg/kg ip 65+13mg/kg, ip 2% inhalation
Data resource Uechi et al. 1998 Odashima et al. 2007 Ma et al. 2002 Vatner et al. 2000 Janssen et al. 2004

All values are mean±SE. The heart rate and arterial pressure in conscious mice were much higher than those seen in anesthetized mice. (K=ketamine, X=xylazine; HR=heart rate; IP=intraperitoneal injection, IM=intramuscular injection, SC=subcutaneous injection).