Table 4.

Odds ratios^a (95% CI) for progression of cerebral ischemic burden as a function of cumulative diabetes or cumulative hypertension

Abbreviations: CI = confidence interval; OR = odds ratio.

^aModel 1: adjusted for age (continuous), sex, and race. Model 2: adjusted for age (continuous), sex, race, and diabetes mellitus or hypertension. Model 3: adjusted for age (continuous), sex, race, diabetes mellitus or hypertension, APOE, prevalent stroke, and incident stroke.

^bOne or more grades of change in imaging features vs none: Atherosclerosis Risk in Communities MRI study.

^cp < 0.05.