Table 2.

Additional aspects of HCC management for potential evaluation using data from the HCC BRIDGE China national study.

Outcomes in patient subpopulations

• Assessment of treatment use and clinical outcomes among patients with:

◦ Traditional HCC risk factors, such as hepatitis B or hepatitis C virus infection (or co-infection), alcoholic liver disease, or cirrhosis

◦ Diabetes or multiple metabolic disorder

◦ HIV co-infection

• Assessment of the impact of underlying disease management on clinical outcomes in these patients

• Evaluation of potential regional/provincial differences in outcomes among patient subpopulations

Impact of HCC screening

• Assessment of influence of screening on:

◦ Treatment allocation and clinical outcomes

◦ Overall survival

◦ Underlying disease

• Evaluation of the cost-effectiveness of mandatory HCC screening

Health care access

• Evaluation of the level of health care access in different regions/provinces and association with clinical outcomes

• Examination of any potential influence of immigrant/minority status, risk factor status, and alcohol and drug use on health care access