Table 5. Pharmacokinetics of MS-0022.
Cmax, ng/ml | AUClast ng*min/ml | AUCinf ng*min/ml | T1/2, min | Kel, min-1 | |
IV | 934.3 | 87683.5 | 93897.6 | 59.27 | 0.0117 |
IP | 377.7 | 25025.0 | 26237.8 | 54.83 | 0.0126 |
PO | 912.0 | 64177.5 | 68526.0 | 59.10 | 0.0117 |
Pharmacokinetic profile of MS-0022 by IV, IP and PO administration in mice. The table displays the maximum concentration (Cmax), total drug exposure (AUClast) and (AUCinf), half-life (T1/2) and terminal slope (Kel).