Figure 1. Compiled urinary protein profiles of female Fabry patients (a) and healthy controls (b) included in the training cohort.

Normalized MS molecular weight (800–20,000 Da) in logarithmic scale is plotted against normalized CE migration time (18–45 min). The mean signal intensity of polypeptides is given as peak height. 3-D contour plots of the 64 diagnostic markers in the Fabry (c) and healthy control (d) patient cohort with 5× zoom compared to (a) and (b).