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. 2011 Jun 15;6(6):e21018. doi: 10.1371/journal.pone.0021018

Table 1. Panel of chimeric rabbit/human Fab selected by phage display.

Clone1 Library Panning rounds Repeated clones Binding
hROR1ECD Fc-hROR1 hROR1ECD2 Fc-hROR12 HEK 293F/hROR13
R11 R 4 0 26/31 ++ ++ +
R12 R 4 0 1/31 ++ ++ ++
Y4 Y 4 0 2/31 ++
Y13 Y 4 0 14/31 ++
Y14 Y 4 0 2/31 +
Y27 Y 4 0 13/31 ++
Y31 Y 3 1 4/4 + + +
1

Defined by unique DNA fingerprint and sequence.

2

As measured by ELISA.

3

As measured by flow cytometry.