Table 3. Two-gene models identified by STEP analysis.

Model	R2	Detection rate of control individuals (%)	Detection rate of melanoma patients (%)
PLEK2-C1QB model	0.728	90.0	93.3
PLEK2-TMOD1 model	0.701	88.0	93.3
PLEK2-PLXDC2 model	0.701	88.0	93.3
PLEK2-TSPAN5 model	0.670	90.0	93.3
PLEK2-C20ORF108 model	0.662	92.0	86.7
PLEK2-GLRX5 model	0.661	90.0	88.9
PLEK2-GYPA model	0.650	88.0	91.1
PLEK2-SLC4A1 model	0.623	88.0	91.1
PLEK2-IL-1R2 model	0.621	88.0	88.9
PLEK2-BLVRB model	0.619	90.0	91.1
PLEK2-GYPB model	0.619	86.0	84.4
PLEK2-PBX1 model	0.611	88.0	86.7
PLEK2-PTPRK model	0.610	90.0	86.7
PLEK2-PLAUR model	0.603	84.0	84.4
PLEK2-CXCL16 model	0.603	88.0	88.9
PLEK2-CNKSR2 model	0.602	88.0	86.7
PLEK2-SCN3A model	0.602	86.0	86.7
PLEK2-LARGE model	0.602	88.0	84.4
PLEK2 (1-gene model)	0.560	84.0	86.7