Table 2. Univariate and Multivariate Analysis of Overall 3 year Survival in Patients with Pancreatic Ductal Adenocarcinoma.
| Univariate analysis | Multivariate analysis | |||||
| Variable | HR (95%CI) | P | HR (95%CI) | P | ||
| Marital Status | ||||||
| Unmarried | 1.00 | 1.00 | ||||
| Married | 0.83 | (0.82–0.85) | <0.0001 | 0.87 | (0.85–0.89) | <0.0001 |
| Sex | ||||||
| Men | 1.00 | 1.00 | ||||
| Women | 0.97 | (0.95–0.99) | 0.0100 | 0.91 | (0.89–0.94) | <0.0001 |
| Race | ||||||
| White | 1.00 | 1.00 | ||||
| Black | 1.12 | (1.08–1.16) | <0.0001 | 1.12 | (1.08–1.16) | <0.0001 |
| Other* ≠ | 1.00 | (0.96–1.04) | 0.8869 | 0.99 | (0.94–1.03) | 0.4988 |
| Age at Diagnosis | ||||||
| <60 | 1.00 | 1.00 | ||||
| 60–74 | 1.28 | (1.25–1.32) | <0.0001 | 1.30 | (1.26–1.34) | <0.0001 |
| >74 | 1.67 | (1.62–1.72) | <0.0001 | 1.63 | (1.58–1.68) | <0.0001 |
| Year of Diagnosis | ||||||
| 2001–2003 | 1.00 | 1.00 | ||||
| 1998–2000 | 1.05 | (1.02–1.08) | 0.0014 | 1.05 | (1.02–1.08) | 0.001 |
| 1993–1997 | 1.12 | (1.09–1.15) | <0.0001 | 1.13 | (1.10–1.16) | <0.0001 |
| 1988–1992 | 1.17 | (1.12–1.20) | <0.0001 | 1.19 | (1.15–1.22) | <0.0001 |
| Cancer Directed Surgery | ||||||
| None | 1.00 | 1.00 | ||||
| Surgery | 0.34 | (0.32–0.35) | <0.0001 | 0.46 | (0.4–0.48) | <0.0001 |
| Radiation Therapy | ||||||
| None | 1.00 | 1.00 | ||||
| EBRT | 0.56 | (0.54–0.57) | <0.0001 | 0.72 | (0.70–0.74) | <0.0001 |
| Stage | ||||||
| Localized | 1.00 | 1.00 | ||||
| Regional | 1.13 | (1.08–1.18) | <0.0001 | 1.21 | (1.16–1.27) | <0.0001 |
| Distant | 2.23 | (2.13–2.33) | <0.0001 | 1.83 | (1.75–1.91) | <0.0001 |
HR indicates hazard ratio; CI indicates confidence interval; EBRT, external beam radiation therapy; A race of Other indicates Asian, or Asian-Pacific Islander.
*Variable shown to not be predictive of survival in univariate analysis.
≠Variable shown to not be predictive of survival in multivariate analysis.