Figure 7. Endplates from dt^27J mice are poorly developed.

Representative photomicrographs showing NMJ endplate morphology in TA muscle at P15 from wild type (A–E) and dt^27J (A'–E') mice. dt^27J TA muscles show more immature NMJs (A'–B') when compared to wild type (A–E). The endplate morphology included two different patterns frequently observed – an elongated form with domains (D and D') and oval-like form with domains (E and E'). Scale bar, 15 µm. F. Graphical representation showing the percentage of immature endplates in TA and EDL muscles from wild type (n = 5) and dt^27J (n = 5) mice at P15 (**p<0.01, student t-test).