Figure 9. TA myofiber atrophy in dt^27J mice at P15.

TA myofibers in cross-section were stained with hematoxylin and eosin. A. Healthy myofibers from TA wild type muscle were observed under light microscopy. B. Myofiber atrophy in TA dt^27J muscle is observed. Myofibers are smaller and many more nuclei are visible. C. A graphical representation showing the TA muscle fiber area in µm² from wild type (n = 6) and dt^27J (n = 6) mice revealed muscle atrophy in dt^27J mice (** p<0.01, student t-test). Scale bars (A, B), 100 µm.