Figure 2. Elevated plus maze test.

Number of total entries (A), percentage of entries into open arms (B), total distance traveled during the test (C), percentage of time on open arms (D). Percentages of entries into open arms and of time in open arms were significantly increased in tauopathy model mice, respectively. Three wild type mice and 2 tauopathy model mice dropped from the open arms and failed to complete the task. Controls: wild type mice (n = 16); Mutants: tauopathy model mice (n = 15). Tested with Student's t-test.