Table 4.
Numerical abnormalities in MII spermatocytes after exposure of male mice to ET
| Dose, mg/kg | Harvest time | Aneuploidy
|
Diploidy (N =
40)
|
||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Total no. spermatocytes | Hypohaploidy
(N = 16–19)
|
Haploidy
(N = 20)
|
Hyperhaploidy
(N = 21)
|
Total no. spermatocytes | No. | % | |||||
| No. | % | No. | % | No. | % | ||||||
| 0 | 257 | 28 | 10.9 ± 2.9 | 228 | 88.7 | 1 | 0.4 ± 0.4 | 268 | 11 | 4.1 ± 1.4 | |
| 80 | 6 h | 184 | 15 | 8.2 ± 2.3 | 169 | 91.8 | 0 | 0 | 189 | 5 | 2.6 ± 0.8 |
| 80 | 16 h | 164 | 27 | 16.5 ± 4.8 | 127 | 77.4 | 10 | 6.1 ± 2.3* | 187 | 23 | 12.3 ± 3.5* |
| 80 | 40 h | 111 | 16 | 14.4 ± 3.1 | 87 | 78.4 | 8 | 7.2 ± 1.9* | 137 | 26 | 19.0 ± 4.5* |
| 80 | 64 h | 177 | 21 | 11.9 ± 3.4 | 153 | 86.4 | 3 | 1.7 ± 1.0 | 195 | 18 | 9.2 ± 0.9* |
| 80 | 10 d | 211 | 43 | 20.4 ± 3.1 | 167 | 79.1 | 1 | 0.5 ± 0.5 | 217 | 6 | 2.8 ± 1.2 |
Results are presented ±SE. *, P < 0.01 vs. controls (χ2).