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. 2001 Mar 13;98(7):3952–3957. doi: 10.1073/pnas.061404598

Table 5.

Effect of ET treatment of male germ cells on fertilization rate and zygotic development

Dose, mg/kg Days post ET No. eggs Fertilized eggs*
First-cleavage metaphases
No. % No. %
0 698 568 81.4  ± 2.1 459 80.8  ± 4.9
80 6.5 627 522 83.3  ± 3.9 451 86.4  ± 9.7
80 24.5 835 630 75.4  ± 2.0 486 77.1  ± 8.2
80 34.5 318 242 76.1  ± 3.2 201 83.1  ± 8.0
80 41.5 321 233 72.6  ± 12.8 188 80.7  ± 9.4

Results are presented ± SE. 

*

Fertilization rate, indicator of prefertilization toxicity. 

Zygotic development (first-cleavage metaphases/fertilized eggs), indicator of postfertilization toxicity. 

P < 0.01 vs. controls (χ2).