. Author manuscript; available in PMC: 2012 Jul 1.

Published in final edited form as: Pharmacogenet Genomics. 2011 Jul;21(7):388–396. doi: 10.1097/FPC.0b013e32834632e4

Table 6.

False positive reporting probability values for associations between the combined genotypes of MDM4 polymorphisms and oropharyngeal cancer risk

Prior probability	Oropharyngeal cancer		Oropharyngeal cancer with T1–2		Oropharyngeal cancer with regional lymph nodes		Oropharyngeal cancer with stage III–IV

	Observed OR^a	Expected OR^b	Observed OR^a	Expected OR^b	Observed OR^a	Expected OR^b	Observed OR^a	Expected OR^b

	1.32	1.5	1.40	1.5	1.44	1.5	1.34	1.5

0.25	0.220	0.152	0.079	0.148	0.186	0.066	0.207	0.148
0.1	0.458	0.350	0.204	0.343	0.407	0.175	0.439	0.342
0.01	0.903	0.856	0.738	0.852	0.883	0.700	0.896	0.851
0.001	0.990	0.984	0.966	0.983	0.987	0.959	0.989	0.983
0.0001	1.000	0.998	0.999	0.998	0.999	0.996	0.999	0.998

Calculation of FPRP using the observed OR with the common combined genotypes.

Calculation of FPRP using study subjects to detect an OR of 1.5 with the common combined genotypes.