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Tr1-cell lines express activating KIRsa)
| Th0 HD1 | Tr1 HD1 | Th0 HD2 | Tr1 HD2 | |
|---|---|---|---|---|
| KIR2DL4 | + | + | + | + |
| KIR2DS1 | − | − | + | − |
| KIR2DS2 | + | + | + | + |
| KIR2DS3 | + | + | − | − |
| KIR2DS4 | − | − | − | − |
| KIR2DS5 | − | − | − | − |
| KIR3DS1 | − | − | + | + |
mRNA expression of human activating KIR genes was assessed in Th0 and Tr1 T-cell lines by KIR typing. Clear visibility (+) or absence (−) of KIR-specific PCR products of two distinct donors tested are shown.
