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. 2011 May 18;12(5):3250–3262. doi: 10.3390/ijms12053250

Table 1.

The results of different pharmacophore models.

Compounds Used as a Template True Positive Rate True Negative Rate
BHF, TMI 61.5% 85.2%
BHF, Chrysin and Tanshinone IIA 69.2% 96.8%
Chrysin, Psoralen and Dracorhodin 61.5% 89.9%
Three TMI in different conformations without optimization 84.6% 77.2%
Three TMI in different conformations with sophisticated optimization 84.6% 86.8%